Sources and evidence

External sources inform LiverWare's educational content. This page lists the core public references behind the project's current MASLD information.

How to read this evidence

External guidelines do not make LiverWare a validated diagnostic instrument.

Users should review important personal health questions with a licensed professional. LiverWare's educational content is not a substitute for professional medical advice.

Core public reference list

EASL-EASD-EASO Clinical Practice Guidelines on the Management of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Published in 2024 by the European Association for the Study of the Liver, the European Association for the Study of Diabetes, and the European Association for the Study of Obesity. LiverWare uses it for the cardiometabolic screening criteria, the waist circumference cutoffs for Asian adults, the use of FIB-4 as a first-step fibrosis estimate, and the 12, 6, and 3 month follow-up intervals behind its reassessment reminders.

Read on EASL View the PubMed record

A multi-society Delphi consensus statement on new fatty liver disease nomenclature

Rinella and colleagues, 2023. This consensus replaced the term NAFLD with MASLD and defined it as liver fat together with at least one of five cardiometabolic risk factors. LiverWare uses it for the definitions behind the blood sugar (fasting glucose above 100 mg/dL), blood pressure (130/85 mmHg or treatment), and blood fat (triglycerides above 150 mg/dL, low HDL cholesterol) sections.

View the PubMed record

Other standards used in the screening

WHO BMI classification. The body mass index cutoff of 25.0 kg/m² follows the World Health Organization's general adult classification.
AUDIT-C. A standard three-question alcohol screening tool. LiverWare uses its sex-specific flag levels (4 or more for men, 3 or more for women) as a separate alcohol flag, never as part of the score.
FIB-4 index. Calculated from age, AST, ALT, and platelet count, with published cutoffs of 1.30 and 2.67 (2.0 as the lower cutoff for adults 65 and older).
Consulting physicians. Lifestyle criteria and boundary values are reviewed with consulting physicians.

Scope of this list

This is a core public reference list, not a complete export of Livvy's internal knowledge corpus. It is maintained as static public information and does not query Livvy's source records.